Teratogens
The following table includes some of the drugs and medical conditions that may harm a developing fetus:
| Drug/condition | Effect |
|---|---|
| ACE inhibitors | Renal dysgenesis Craniofacial abnormalities |
| Alcohol | Craniofacial abnormalities |
| Aminoglycosides | Ototoxicity |
| Carbamazepine | Neural tube defects Craniofacial abnormalities |
| Chloramphenicol | 'Grey baby' syndrome |
| Cocaine | Intrauterine growth retardation Preterm labour |
| Diethylstilbesterol | Vaginal clear cell adenocarcinoma |
| Lithium | Ebstein's anomaly (atrialized right ventricle) |
| Maternal diabetes mellitus | Macrosomia Neural tube defects Polyhydramnios Preterm labour Caudal regression syndrome |
| Smoking | Preterm labour Intrauterine growth retardation |
| Tetracyclines | Discoloured teeth |
| Thalidomide | Limb reduction defects |
| Valproate | Neural tube defects Craniofacial abnormalities |
| Warfarin | Craniofacial abnormalities |