MRCEM Notes

Korsakoff's syndrome

Overview
  • marked memory disorder often seen in alcoholics
  • thiamine deficiency causes damage and haemorrhage to the mammillary bodies of the hypothalamus and the medial thalamus
  • in often follows on from untreated Wernicke's encephalopathy

Features
  • anterograde amnesia: inability to acquire new memories
  • retrograde amnesia
  • confabulation

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