MRCEM Notes

Cardiovascular physiology: S1 heart sound

S1 is caused by closure of mitral and tricuspid valves

Causes of a loud S1
  • mitral stenosis
  • left to right shunts
  • short PR interval, atrial premature beats
  • hyperdynamic states

Causes of a quiet S1
  • mitral regurgitation


The diagram below demonstrates the cardiac cycle in relation to the heart sounds.
Full-size image