Thyrotoxicosis
Graves' disease accounts for around 70% of cases of thyrotoxicosis.
Causes
Investigation
Causes
- Graves' disease
- toxic nodular goitre
- acute phase of subacute (de Quervain's) thyroiditis
- acute phase of post-partum thyroiditis
- acute phase of Hashimoto's thyroiditis (later results in hypothyroidism)
- amiodarone therapy
Investigation
- TSH down, T4 and T3 up
- thyroid autoantibodies
- other investigations are not routinely done but includes isotope scanning
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Venn diagram showing how different causes of thyroid dysfunction may manifest. Note how many causes of hypothyroidism may have an initial thyrotoxic phase.
