<i>Helicobacter pylori</i>
Helicobacter pylori is a Gram negative bacteria associated with a variety of gastrointestinal problems, principally peptic ulcer disease
Associations
The role of H pylori in Gastro-oesophageal reflux disease (GORD) is unclear - there is currently no role in GORD for the eradication of H pylori
Management - eradication may be achieved with a 7 day course of
Associations
- peptic ulcer disease (95% of duodenal ulcers, 75% of gastric ulcers)
- gastric cancer
- B cell lymphoma of MALT tissue (eradication of H pylori results causes regression in 80% of patients)
- atrophic gastritis
The role of H pylori in Gastro-oesophageal reflux disease (GORD) is unclear - there is currently no role in GORD for the eradication of H pylori
Management - eradication may be achieved with a 7 day course of
- a proton pump inhibitor + amoxicillin + clarithromycin, or
- a proton pump inhibitor + metronidazole + clarithromycin
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H. pylori colonized on the surface of regenerative epithelium (silver stain)