Hodgkin's lymphoma

Hodgkin's lymphoma is a malignant proliferation of lymphocytes characterised by the presence of the Reed-Sternberg cell. It has a bimodal age distributions being most common in the third and seventh decades

Features

• lymphadenopathy (75%) - painless, non-tender, asymmetrical
• systemic (25%): weight loss, pruritus, night sweats, fever (Pel-Ebstein)
• alcohol pain in HL
• normocytic anaemia, eosinophilia
• LDH raised