MRCEM Notes

Dermatitis herpetiformis

Dermatitis herpetiformis is an autoimmune blistering skin disorder associated with coeliac disease. It is caused by deposition of IgA in the dermis.

Features
  • itchy, vesicular skin lesions on the extensor surfaces (e.g. elbows, knees, buttocks)

Diagnosis
  • skin biopsy: direct immunofluorescence shows deposition of IgA in a granular pattern in the upper dermis

Management
  • gluten-free diet
  • dapsone

© Image used on license from DermNet NZ and with the kind permission of Prof Raimo Suhonen

© Image used on license from DermNet NZ
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