MRCEM Notes

Measles

Measles Key Points

  • RNA paramyxovirus
  • Spread via aerosol transmission (droplets)
  • incubation period = 10-14 days
  • Patients are infectious from 4 days before the rash to 4 days after.
  • Pneumonia, otitis media and encephalopathy are well documented complications.
  • SSPE is a rare fatal complication

Features
  • prodrome: irritable, conjunctivitis, fever
  • Koplik spots (before rash): white spots ('grain of salt') on buccal mucosa
  • rash: starts behind ears then to whole body, discrete maculopapular rash becoming blotchy & confluent

© Image used on license from DermNet NZ
Koplik spots

Complications
  • encephalitis: typically occurs 1-2 weeks following the onset of the illness)
  • subacute sclerosing panencephalitis: very rare, may present 5-10 years following the illness
  • febrile convulsions
  • giant cell pneumonia
  • keratoconjunctivitis, corneal ulceration
  • diarrhoea
  • increased incidence of appendicitis
  • myocarditis

© Image used on license from DermNet NZ
The rash typically starts behind the ears and then spreads to the whole body

Management of contacts
  • if a child not immunized against measles comes into contact with measles then MMR should be offered (vaccine-induced measles antibody develops more rapidly than that following natural infection)
  • this should be given within 72 hours
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