MRCEM Notes

Lumbar puncture

Lumbar Puncture Key Points


  • An LP should be performed at the L3/L4 or L4/L5 space as the spinal cord terminates at L1-L2
  • The first 'give' of the needle is when the ligamentum flavum is pierced and the second 'give' is when the dura is pierced
  • Normal opening pressure is between 10-25 cm H2O in an adult
  • Post procedure headache is common (up to 38%)

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Layers pierced during lumbar puncture:
  • Skin
  • Subcutaneous tissue (fat and fascia)
  • Supraspinous ligament
  • Interspinous ligament
  • Ligamentum flavum
  • Extradural space
  • Dura mater
  • Subdural space
  • Arachnoid mater
  • Subarachnoid space
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