Herpes
There are 8 human herpes viruses (HHV).
- Herpes simplex type I (HSV1/HHV-1)
- Herpes simplex type II (HSV2/HHV-2)
- Varicella-zoster virus (VZV/HHV-3)
- Epstein-Barr virus (EBV/HHV-4)
- Cytomegalovirus (CMV/HHV-5)
- Human herpes virus type 6 (HBLV/HHV-6)
- Human herpes virus type 7 (HHV-7)
- Kaposi's sarcoma herpes virus (KSHV/HHV-8)
| Virus Name | HHV Number | Clinical Diseases |
|---|---|---|
| Herpes simplex virus type 1 | HHV-1 | Oral herpes, gingivostomatitis, keratoconjunctivitis, encephalitis, now recognised as the most common cause of genital herpes |
| Herpes simplex virus type 2 | HHV-2 | Classically genital herpes, neonatal herpes, aseptic meningitis |
| Varicella-zoster virus | HHV-3 | Chickenpox (varicella), shingles (herpes zoster), post-herpetic neuralgia |
| Epstein-Barr virus | HHV-4 | Infectious mononucleosis, Burkitt lymphoma, nasopharyngeal carcinoma, Hodgkin lymphoma |
| Cytomegalovirus | HHV-5 | Congenital CMV infection, CMV mononucleosis, CMV retinitis (especially in HIV) |
| Human herpesvirus 6 | HHV-6 | Roseola infantum (exanthem subitum), febrile seizures in infants |
| Human herpesvirus 7 | HHV-7 | Occasionally roseola, less well defined role in disease |
| Kaposi’s sarcoma–associated herpesvirus | HHV-8 | Kaposi’s sarcoma, primary effusion lymphoma, Castleman disease |