MRCEM Notes

Sildenafil

Sildenafil is a phosphodiesterase type V inhibitor used in the treatment of impotence.

Contraindications
  • patients taking nitrates and related drugs such as nicorandil
  • hypotension
  • recent stroke or myocardial infarction (NICE recommend waiting 6 months)

Side-effects
  • visual disturbances e.g. blue discolouration, non-arteritic anterior ischaemic neuropathy
  • nasal congestion
  • flushing
  • gastrointestinal side-effects
  • headache

The blue pill, Viagra (sildenafil), causes blue discolouration of vision
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