Aortic regurgitation
Features
Causes (due to valve disease)
Causes (due to aortic root disease)
- early diastolic murmur
- collapsing pulse
- wide pulse pressure
- mid-diastolic Austin-Flint murmur in severe AR - due to partial closure of the anterior mitral valve cusps caused by the regurgitation streams
Causes (due to valve disease)
- rheumatic fever
- infective endocarditis
- connective tissue diseases e.g. RA/SLE
- bicuspid aortic valve
Causes (due to aortic root disease)
- aortic dissection
- spondylarthropathies (e.g. ankylosing spondylitis)
- hypertension
- syphilis
- Marfan's, Ehler-Danlos syndrome