MRCEM Notes

Horner's syndrome

Features
  • miosis (small pupil)
  • ptosis
  • enophthalmos* (sunken eye)
  • anhidrosis (loss of sweating one side)

Distinguishing between causes
  • heterochromia (difference in iris colour) is seen in congenital Horner's
  • anhidrosis: see below

Central lesionsPre-ganglionic lesionsPost-ganglionic lesions
Anhidrosis of the face, arm and trunkAnhidrosis of the faceNo anhidrosis
Stroke
Syringomyelia
Multiple sclerosis
Tumour
Encephalitis
Pancoast's tumour
Thyroidectomy
Trauma
Cervical rib
Carotid artery dissection
Carotid aneurysm
Cavernous sinus thrombosis
Cluster headache

*in reality the appearance is due to a narrow palpebral aperture rather than true enophthalmos
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