The table below shows the rate-determining enzymes involved in common metabolic processes:
| Process | Enzyme |
|---|
| TCA cycle | Isocitrate dehydrogenase |
| Glycolysis | Phosphofructosekinase-1 |
| Gluconeogenesis | Fructose-1,6-biphosphatase |
| Glycogenesis | Glycogen synthase |
| Glycogenolysis | Glycogen phosphorylase |
| Pentose phosphate pathway | Glucose-6-phosphate dehydrogenase |
| Lipogenesis | Acetyl-CoA carboxylase |
| Lipolysis | Carnitine-palmitoyl transferase I |
| Cholesterol synthesis | HMG-CoA reductase |
| Ketogenesis | HMG-CoA synthase |
| Urea cycle | Carbamoyl phosphate synthetase I |
| De novo pyrimidine synthesis | Carbamoyl phosphate synthetase II |
| De novo purine synthesis | Glutamine-PRPP amidotransferase |