MRCEM Notes

Osteoarthritis and rheumatoid arthritis: comparison

OsteoarthritisRheumatoid arthritis
AetiologyMechanical - wear & tear*
  • localised loss of cartilage
  • remodeling of adjacent bone
  • associated inflammation
Autoimmune
GenderSimilar incidence in men and womenMore common in women
AgeSeen most commonly in the elderlySeen in adults of all ages
Typical affected jointsLarge weight bearing joints (hip, knee)
Carpometacarpal joint
DIP, PIP joints
MCP, PIP joints
Typical historyPain following use, improves with rest
Unilateral symptoms
No systemic upset
Morning stiffness, improves with use
Bilateral symptoms
Systemic upset
X-ray findingsLoss of joint space
Subchondral sclerosis
Subchondral cysts
Osteophytes forming at joint margins
Loss of joint space
Juxta-articular osteoporosis
Periarticular erosions
Subluxation

*it is sometimes better to use the term 'wear & repair' to patients
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