MRCEM Notes

Asthma: acute severe

Patients with acute severe asthma are stratified into moderate, severe or life-threatening

ModerateSevereLife-threatening
PEFR 50-75% best or predicted
Speech normal
RR < 25 / min
Pulse < 110 bpm
PEFR 33 - 50% best or predicted
Can't complete sentences
RR > 25/min
Pulse > 110 bpm
PEFR < 33% best or predicted
Oxygen sats < 92%
Silent chest, cyanosis or feeble respiratory effort
Bradycardia, dysrhythmia or hypotension
Exhaustion, confusion or coma

Note that a patient having any one of the life-threatening features should be treated as having a life-threatening attack.

British Thoracic Society guidelines
  • magnesium sulphate recommended as next step for patients who are not responding (e.g. 1.2 - 2g IV over 20 mins)
  • little evidence to support use of IV aminophylline (although still mentioned in management plans)
  • if no response consider IV salbutamol
Full-size image