Hypercalcaemia: causes
The most common causes of hypercalcaemia are malignancy (bone metastases, myeloma, PTHrP from squamous cell lung cancer) and primary hyperparathyroidism
Other causes include
*other causes of granulomas may lead to hypercalcaemia e.g. Tuberculosis and histoplasmosis
**usually normal in this condition but hypercalcaemia may occur with prolonged immobilisation
Other causes include
- sarcoidosis*
- vitamin D intoxication
- acromegaly
- thyrotoxicosis
- Milk-alkali syndrome
- drugs: thiazides, calcium containing antacids
- dehydration
- Addison's disease
- Paget's disease of the bone**
*other causes of granulomas may lead to hypercalcaemia e.g. Tuberculosis and histoplasmosis
**usually normal in this condition but hypercalcaemia may occur with prolonged immobilisation