MRCEM Notes

Ascending cholangitis

Ascending cholangitis is a bacterial infection of the biliary tree. The most common predisposing factor is gallstones.

Charcot's triad of right upper quadrant (RUQ) pain, fever and jaundice occurs in about 20-50% of patients
  • fever is the most common feature, seen in 90% of patients
  • RUQ pain 70%
  • jaundice 60%
  • hypotension and confusion are also common

Management
  • intravenous antibiotics
  • endoscopic retrograde cholangiopancreatography (ERCP) after 24-48 hours to relieve any obstruction
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