MRCEM Notes

Urinary tract infection in adults: management

Lower urinary tract infections


Non-pregnant women
  • local antibiotic guidelines should be followed if available
  • 2012 SIGN guidelines recommend trimethoprim or nitrofurantoin for 3 days

Pregnant women with symptomatic bacteriuria should be treated with an antibiotic for 7 days. A urine culture should be sent. For asymptomatic pregnant women:
  • a urine culture should be performed routinely at the first antenatal visit
  • if positive, a second urine culture should be sent to confirm the presence of bacteriuria
  • SIGN recommend to treat asymptomatic bacteriuria detected during pregnancy with an antibiotic
  • a 7 day course of antibiotics should be given
  • a further urine culture should be sent following completion of treatment as a test of cure


Acute pyelonephritis

For patients with sign of acute pyelonephritis hospital admission should be considered
  • local antibiotic guidelines should be followed if available
  • the BNF currently recommends a broad-spectrum cephalosporin or a quinolone (for non-pregnant women) for 10-14 days
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