MRCEM Notes

Postpartum haemorrhage

Postpartum haemorrhage (PPH) is defined as blood loss of > 500mls and may be primary or secondary

Primary PPH
  • occurs within 24 hours
  • affects around 5-7% of deliveries
  • most common cause of PPH is uterine atony (90% of cases). Other causes include genital trauma and clotting factors

Risk factors for primary PPH include*:
  • previous PPH
  • prolonged labour
  • pre-eclampsia
  • increased maternal age
  • polyhydramnios
  • emergency Caesarean section
  • placenta praevia, placenta accreta
  • macrosomia
  • ritodrine (a beta-2 adrenergic receptor agonist used for tocolysis)

Management
  • ABC
  • IV syntocinon (oxytocin) 10 units or IV ergometrine 500 micrograms
  • IM carboprost
  • other options include: B-Lynch suture, ligation of the uterine arteries or internal iliac arteries
  • if severe, uncontrolled haemorrhage then a hysterectomy is sometimes performed as a life-saving procedure

Secondary PPH
  • occurs between 24 hours - 12 weeks**
  • due to retained placental tissue or endometritis

*the effect of parity on the risk of PPH is complicated. It was previously though multiparity was a risk factor but more modern studies suggest nulliparity is actually a risk factor

**previously the definition of secondary PPH was 24 hours - 6 weeks. Please see the RCOG guidelines for more details
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