Congenital infections
The major congenital infections encountered in examinations are rubella, toxoplasmosis and cytomegalovirus
Cytomegalovirus is the most common congenital infection in the UK. Maternal infection is usually asymptomatic
Cytomegalovirus is the most common congenital infection in the UK. Maternal infection is usually asymptomatic
| Rubella | Toxoplasmosis | Cytomegalovirus | |
|---|---|---|---|
| Characteristic features | Sensorineural deafness Congenital cataracts Congenital heart disease (e.g. patent ductus arteriosus) Glaucoma | Cerebral calcification Chorioretinitis Hydrocephalus | Growth retardation Purpuric skin lesions |
| Other features | Growth retardation Hepatosplenomegaly Purpuric skin lesions 'Salt and pepper' chorioretinitis Microphthalmia Cerebral palsy | Anaemia Hepatosplenomegaly Cerebral palsy | Sensorineural deafness Encephalitis/seizures Pneumonitis Hepatosplenomegaly Anaemia Jaundice Cerebral palsy |