MRCEM Notes

Roseola infantum

Roseola infantum (also known as exanthem subitum, occasionally sixth disease) is a common disease of infancy caused by the human herpes virus 6 (HHV6). It has an incubation period of 5-15 days and typically affects children aged 6 months to 2 years.

Features
  • high fever: lasting a few days, followed by a
  • maculopapular rash
  • febrile convulsions occur in around 10-15%
  • diarrhoea and cough are also commonly seen

Other possible consequences of HHV6 infection
  • aseptic meningitis
  • hepatitis
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