MRCEM Notes

Cerebral ventricles

The ventricular system of the brain consists of four interconnected cavities called cerebral ventricles. The ventricular system is continuous with the central canal of the spinal cord communicating with the spinal cord via the fourth ventricle.

Each ventricle contains specialised cells called the choroid plexus which produces cerebrospinal fluid (CSF). The ventricular system and the central canal of the spinal cord are lined with another type of specialised epithelial cell, called ependyma, that are connected by tight junctions which maintain the blood-cerebrospinal fluid barrier.

Illustration of the anatomy of the cerebral ventricles. Click on image to enlarge

The ventricles are connected by channels called foramina. CSF flows between the ventricles via these foramina. The interventricular foramina (AKA foramina of Monro) connects the lateral ventricles to the third ventricle whilst the cerebral aqueduct (aqueduct of Sylvius) connects the third and fourth ventricles. the foramina are summarised in the table below:

ForaminaOriginDestination
Interventricular foramina (Monro)Lateral ventriclesThird ventricle
Cerebral aqueduct (Sylvius)Third ventricleFourth ventricle
Median aperture (Magendie)Fourth ventricleSubarachnoid space via cisterna magna
Right & left lateral aperture (Luschka)Fourth ventricleSubarachnoid space via cistern of great cerebral vein
Full-size image